Fig. 7From: Hepatic S1P deficiency lowers plasma cholesterol levels in apoB-containing lipoproteins when LDLR function is compromisedHepatic S1P KD reduced plasma Blp-c levels in LDLR-/- mice. a and b, S1Pf/fLDLR-/- Luci and S1Pf/fLDLR-/-Cre mice. Lipid measurements were carried out on gel filtration fractions from pooled plasma samples of mice in two mouse models of hepatic S1P KD mice. Female mice (N = 4, 6–8 weeks of age) were transduced with the indicated adenoviruses. This experiment was repeated three times and similar results were obtainedBack to article page