Hepatic S1P deficiency lowers plasma cholesterol levels in apoB-containing lipoproteins when LDLR function is compromised

Table 2 Phenotypic comparison of S1P^f/f and L-S1P

Blood was obtained from non-fasted male mice (6–8 weeks of age) as described in Methods. Each value represents the mean ± the SD of five mice. The statistical significance (Student’s t test) between S1P^f/f and L-S1P was calculated. *P < 0.05; and **P < 0.01. ^afull length S1P mRNA expression is expressed as a % of the corresponding S1P^f/f value

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