Fig. 2From: FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesityFXR was downregulated in the kidneys of offspring of obese mothers at postnatal Days 1 and 20. mRNA expression of FXR (a) and its downstream target SREBP-1c (b) at postnatal Days 1 and 20 (b). IHC staining (c and e) and quantification (d and f) of FXR and SREBP1c at Day 20. Images shown at 400x magnification. N = 5–7 per group, *p < 0.05 and **P < 0.01Back to article page