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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity

Fig. 2

FXR was downregulated in the kidneys of offspring of obese mothers at postnatal Days 1 and 20. mRNA expression of FXR (a) and its downstream target SREBP-1c (b) at postnatal Days 1 and 20 (b). IHC staining (c and e) and quantification (d and f) of FXR and SREBP1c at Day 20. Images shown at 400x magnification. N = 5–7 per group, *p < 0.05 and **P < 0.01

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