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Fig. 4 | Nutrition & Metabolism

Fig. 4

From: FXR expression is associated with dysregulated glucose and lipid levels in the offspring kidney induced by maternal obesity

Fig. 4

Effect of high glucose on FXR expression in HK-2 cells. HK-2 cells were exposed to 5 mM D-glucose (white open bar) or 30 mM D-glucose (black solid bar) for 24 or 72 h. mRNAexpression of FXR (a), SREBP-1c (c) and SHP (e) is shown at 24 and 72 h. Protein expression of FXR (b) and SREBP1 (d) is also shown at 24 and 48 h. N = 3 per group, *p <0.05, **p <0.01, ***p <0.001

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