Fig. 5

Time course data for plasma glucose at baseline, 9-weeks and 18 weeks for inulin (i) and cellulose supplementation (ii). Black line = baseline; dark grey line = 9-week visit; light grey line = 18-week visit. tAUC was calculated using the trapezoid method. ANCOVA using weight change as a covariate was used to analyse delta change between the inulin and cellulose groups. Glucose tAUC delta change at week nine(135 ± 134, n = 17 vs 87 ± 42, n = 17, p = 0.37) or at week 18 (−267 ± 104, n = 17 vs −38 ± 21, n = 17, p = 0.37) did not differ between groups once controlled for weight loss. There was a significant difference in the FPG delta change between groups at week nine once controlled for weight loss (−0.23 ± 0.17 mmol/L, n = 20 vs 0.44 ± 0.24 mmol/L, n = 19, p = 0.005) while the change at week 18 was no longer significant (−0.40 ± 0.19 mmol/L, n = 20 vs 0.16 ± 0.23 mmol/L, n = 18, p = 0.08) (iii). ANCOVA: analysis of covariance; FPG; fasting plasma glucose; tAUC: total area under the curve