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Fig. 6 | Nutrition & Metabolism

Fig. 6

From: A randomized controlled trial: the effect of inulin on weight management and ectopic fat in subjects with prediabetes

Fig. 6

Time course data for plasma insulin at baseline, 9 weeks and 18 weeks for inulin (i) and cellulose supplementation (ii). Black line = baseline; dark grey line = 9-week visit; light grey line. tAUC was calculated using the trapezoid method. ANCOVA using weight change as a covariate was used to analyse delta change between the inulin and cellulose groups. After controlling for weight lost the delta change in insulin tAUC following inulin supplementation was similar to the cellulose group at week nine (−2366 ± 575, n = 17 vs −1566 ± 1724, n = 17, p = 0.66) and week 18 (−2643 ± 671, n = 17 vs −1264 ± 1045, n = 17, p = 0.27). The delta change in fasting insulin was also similar between inulin and cellulose at week nine (−23.3 ± 15.4 pmol/L, n = 18 vs −30.5 ± 17.6 pmol/L, n = 17, p = 0.82) and week 18 (−35.5 ± 17.8 pmol/L, n = 18 vs −14.7 ± 18.7 pmol/L, n = 17, p = 0.53). ANCOVA: analysis of covariance; tAUC: total area under the curve

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