Fig. 3

Muscle protein degradation rates of mice fed a high-fat diet for three or twelve weeks. Soleus (a) and EDL (b) muscles were incubated in Krebs-Henseleit buffer containing cycloheximide, and tyrosine release was measured over time. n = 9–10 per group; *P < 0.05, vs innerv. †P < 0.05 vs control