Fig. 1

Changes in HOMA-IR index, leptin and adiponectin levels in normal-weight, overweight and obese children after a 1 year of lifestyle intervention. HOMA-IR normal weight: P = 0.065, overweight: P = 0.079, obese: P = 0.011. Leptin levels normal weight: P = 0.234, overweight: P = 0.857, obese: P = 0.008. Adiponectin levels normal weight: P = 0.001, overweight: P = 0.002, obese: P < 0.001