Parameters | Normal-weight (n = 28) | Overweight (n = 28) | Obese (n = 27) | ||||||
---|---|---|---|---|---|---|---|---|---|
Baseline | T1-year | P | Baseline | T1-year | P | Baseline | T1-year | P | |
BMI z-score | −0.10 ± 1.03 | −0.16 ± 0.85 | 0.446 | 1.47 ± 0.24 | 1.33 ± 0.44 | 0.021 | 2.18 ± 0.27 | 2.08 ± 0.40 | 0.008 |
FBG (mmol/L) | 4.67 ± 0.38 | 4.63 ± 0.34 | 0.690 | 4.82 ± 0.42 | 4.69 ± 0.42 | 0.047 | 4.95 ± 0.40 | 4.69 ± 0.35 | 0.002 |
HDL-C (mmol/L) | 1.59 ± 0.36 | 1.45 ± 0.31 | <0.001 | 1.21 ± 0.28 | 1.18 ± 0.21 | 0.425 | 1.19 ± 0.29 | 1.14 ± 0.28 | 0.248 |
LDL-C (mmol/L) | 2.61 ± 0.75 | 2.37 ± 0.66 | 0.018 | 2.68 ± 0.59 | 2.48 ± 0.48 | 0.015 | 2.46 ± 0.59 | 2.43 ± 0.47 | 0.410 |
TG (mmol/L) | 0.55 ± 0.26 | 0.56 ± 0.24 | 0.945 | 0.78 ± 0.40 | 0.73 ± 0.39 | 0.682 | 0.86 ± 0.32 | 0.80 ± 0.36 | 0.254 |
Insulin (μU/mL) | 13.4 ± 3.6 | 11.8 ± 6.1 | 0.048 | 19.9 ± 12.5 | 15.8 ± 7.0 | 0.019 | 28.4 ± 13.7 | 26.2 ± 17.7 | 0.019 |
HOMA-IR index | 2.80 ± 0.86 | 2.48 ± 1.37 | 0.065 | 4.18 ± 3.04 | 3.31 ± 1.56 | 0.079 | 6.32 ± 3.19 | 5.53 ± 3.95 | 0.011 |
Leptin (ng/mL) | 6.0 ± 5.19 | 6.78 ± 1.9 | 0.234 | 25.0 ± 13.0 | 25.5 ± 18.1 | 0.857 | 37.7 ± 22.5 | 33.4 ± 24.2 | 0.008 |
Adiponectin (μg/mL) | 6.43 ± 2.51 | 7.98 ± 3.56 | 0.001 | 5.17 ± 2.39 | 6.71 ± 2.77 | 0.002 | 3.96 ± 1.84 | 5.0 ± 2.41 | <0.001 |