Fig. 4

Gene expressions and protein levels in liver after 3 months of D/E diet. a Related gene expressions of lipogenesis in the liver (n = 12); (b) Related gene expressions of β-oxidation in the liver (n = 12); (c) seipin gene expression in liver and WAT (n = 12); (d) Representative Western blot images for the indicated proteins in liver; (e) The quantification by densitometry of PPARα (n = 6); (f) The quantification by densitometry of CPT1α (n = 6); (g) The quantification by densitometry of SCD1 (n = 6). WT, wild type mice; SKO, seipin knockout mice; NC, normal chow diet; D/E, DHA/EPA 3:1 diet. Data are presented as mean ± SEM. *P < 0.05, ***P < 0.001, SKO NC group compared with WT NC group; #P < 0.05, ###P < 0.001, SKO D/E group compared with SKO NC group; $P <0.05, $$P <0.01, $$$P <0.001, WT D/E group compared with WT NC group