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Table 4 Age- and gender-adjusted correlations of plasma amino acid concentrations with obesity and glucose metabolism indices

From: Associations among the plasma amino acid profile, obesity, and glucose metabolism in Japanese adults with normal glucose tolerance

 

Body weight

BMI

WC

VFA

SFA

FPG

2-h PG

HOMA-IR

OGIS

HOMA-β

II

Essential AAs

           

 Histidine

—

—

—

—

—

—

—

—

—

—

—

 Isoleucine

—

—

—

—

—

—

—

—

—

—

—

 Leucine

—

—

—

—

—

—

—

—

—

0.288

—

 Lysine

—

—

—

—

—

—

—

—

—

—

—

 Methionine

—

—

—

—

—

—

—

—

—

—

—

 Phenylalanine

—

—

—

—

—

—

—

—

—

—

—

 Threonine

—

—

—

—

—

—

—

—

—

—

—

 Tryptophan

—

—

—

0.206

—

—

—

—

—

0.259

—

 Valine

0.202

0.247

0.296

—

0.348

—

—

0.380

-

0.272

0.419

Nonessential AAs

          

 Alanine

—

—

0.184

—

—

—

—

—

—

—

—

 Arginine

—

—

—

—

—

—

—

—

—

—

—

 Asparagine

—

—

—

—

—

—

—

—

—

—

—

 α-ABA

—

—

—

—

—

—

—

—

—

—

—

 Citrulline

−0.183

−0.286

−0.358

−0.285

−0.382

—

—

−0.296

-

−0.323

−0.307

 Cystine

—

—

—

—

—

—

—

—

—

—

—

 Glutamate

0.247

0.327

0.352

0.362

0.401

0.395

0.310

0.436

−0.377

0.243

0.403

 Glutamine

−0.265

−0.308

−0.282

−0.233

−0362

—

—

−0395

—

−0.341

−0.434

 Glycine

−0.221

−0.364

−0.316

−0.311

−0.311

—

—

−0.325

0.226

−0.309

−0.380

 Ornithine

—

—

—

—

—

—

—

—

—

—

—

 Proline

—

—

—

—

—

—

—

—

—

—

—

 Serine

—

—

—

—

—

—

—

—

—

−0.280

—

 Taurine

—

—

—

—

—

—

—

—

—

—

—

 Tyrosine

0.164

—

—

—

—

—

—

0.226

−0.238

—

—

  1. Each number indicates a standardized coefficient for two variables that showed significant association in the age- and gender-adjusted multiple logistic regression analysis. AA amino acid, α-ABA α-aminobutyric acid, BMI body mass index, FPG fasting plasma glucose, HOMA-β homeostasis model assessment for β-cell function index, HOMA-IR homeostasis model assessment of insulin resistance, II insulinogenic index, OGIS oral glucose insulin sensitivity, SFA subcutaneous fat area, VFA visceral fat area, WC waist circumference, 2-h PG 2-h plasma glucose