From: Neck circumference as an independent indicator to non-alcoholic fatty liver disease in non-obese men
Men | Women | |||||||
---|---|---|---|---|---|---|---|---|
Normal | Mild | Moderate to severe | P | Normal | Mild | Moderate to severe | P | |
N | 435 | 161 | 148 | 1470 | 310 | 144 | ||
Age (yr) | 52.03 ± 15.06 | 47.81 ± 15.88 | 49.16 ± 15.56 | 0.06 | 48.24 ± 13.80 | 54.55 ± 12.24 | 56.58 ± 10.71 | <0.01 |
Weight (kg) | 61.15 ± 6.42 | 65.03 ± 6.52 | 66.29 ± 6.69 | <0.01 | 54.10 ± 5.42 | 55.95 ± 5.44 | 57.44 ± 4.45 | <0.01 |
Neck circumference (cm) | 34.08 ± 2.16 | 34.78 ± 2.04 | 35.45 ± 2.10 | <0.01 | 30.92 ± 2.25 | 31.33 ± 1.96 | 31.99 ± 2.09 | <0.01 |
Waist circumference (cm) | 76.17 ± 6.60 | 78.43 ± 6.70 | 80.08 ± 6.27 | <0.01 | 71.09 ± 6.85 | 75.08 ± 6.05 | 78.18 ± 6.68 | <0.01 |
Hip circumference (cm) | 89.56 ± 4.66 | 91.77 ± 5.60 | 92.16 ± 5.03 | 0.87 | 89.56 ± 4.73 | 90.39 ± 5.18 | 91.14 ± 4.92 | <0.01 |
Waist to hip ratio | 0.87 ± 0.07 | 0.86 ± 0.07 | 0.87 ± 0.47 | 0.04 | 0.80 ± 0.07 | 0.83 ± 0.07 | 0.86 ± 0.47 | <0.01 |
BMI (kg/m2) | 21.98 ± 1.69 | 22.46 ± 1.70 | 23.13 ± 1.46 | <0.01 | 21.90 ± 1.69 | 22.84 ± 1.46 | 23.48 ± 1.27 | <0.01 |
SBP (mmHg) | 125.74 ± 19.27 | 127.64 ± 17.90 | 129.88 ± 17.83 | 0.06 | 121.98 ± 20.11 | 128.71 ± 19.59 | 133.57 ± 21.48 | <0.01 |
DBP (mmHg) | 76.69 ± 11.64 | 77.24 ± 12.90 | 78.23 ± 12.05 | 0.41 | 72.75 ± 11.69 | 77.01 ± 11.90 | 79.56 ± 12.75 | <0.01 |
FBG (mmol/L) | 5.42 ± 1.36 | 5.29 ± 0.99 | 5.53 ± 1.41 | 0.28 | 5.35 ± 0.93 | 5.62 ± 1.13 | 6.02 ± 1.51 | <0.01 |
Fasting insulin (pmol/L) | 25.6(17.8–33.3) | 27.4(20.0–38.6) | 31.6(22.2–46.4) | <0.01 | 30.1(22.6–40.6) | 33.8(24.7–46.1) | 40.9(29.6–56.5) | <0.01 |
HbA1c (%) | 5.28 ± 0.88 | 5.24 ± 0.70 | 5.43 ± 1.10 | 0.14 | 5.12 ± 0.60 | 5.30 ± 0.73 | 5.48 ± 0.89 | <0.01 |
HOMA-IR | 0.85(0.57–1.17) | 0.90(0.63–1.30) | 1.06(0.73–1.65) | <0.01 | 1.03(0.73–1.39) | 1.17(0.85–1.65) | 1.57(1.12–2.16) | <0.01 |
Total cholerterol (mmol/L) | 4.84 ± 0.92 | 4.70 ± 0.89 | 4.89 ± 1.17 | 0.21 | 4.89 ± 0.93 | 5.15 ± 1.09 | 5.26 ± 0.89 | <0.01 |
LDL-cholesterol (mmol/L) | 2.76 ± 0.66 | 2.82 ± 0.61 | 2.97 ± 0.70 | <0.01 | 2.77 ± 0.69 | 2.94 ± 0.75 | 3.08 ± 0.62 | <0.01 |
HDL-cholesterol (mmol/L) | 1.40 ± 0.28 | 1.32 ± 0.27 | 1.28 ± 0.27 | <0.01 | 1.57 ± 0.30 | 1.50 ± 0.31 | 1.40 ± 0.28 | <0.01 |
Triglycerides (mmol/L) | 1.10(0.87–1.48) | 1.24(0.91–1.76) | 1.50(1.02–2.05) | <0.01 | 1.03(0.77–1.38) | 1.32(0.95–1.77) | 1.77(1.34–2.45) | <0.01 |
Creatinine (umol/L) | 87.01 ± 14.31 | 88.23 ± 12.04 | 90.39 ± 13.16 | 0.03 | 68.75 ± 11.39 | 68.61 ± 11.15 | 69.80 ± 10.33 | 0.53 |
eGFR (ml/min/1.732) | 91.58 ± 17.58 | 91.03 ± 14.85 | 87.82 ± 13.14 | 0.05 | 90.29 ± 16.63 | 88.22 ± 17.42 | 85.04 ± 14.05 | <0.01 |
ALT(U/L) | 19(15–25) | 18(14–25.5) | 22(16–32) | 0.04 | 14(11–19) | 16(13–21) | 20(15–28.5) | <0.01 |
AST (U/L) | 24(20–28) | 22(19–27) | 23(20–30) | <0.01 | 21(18–25) | 22(19–26) | 24(20.5–28) | <0.01 |
Smoker N, (%) | 140(32.18 %) | 53(32.92 %) | 52(35.14 %) | 0.04 | 20(1.36 %) | 2(0.65 %) | 3(2.1 %) | 0.12 |