Fig. 4
From: Leptin receptor signaling is required for high-fat diet-induced atrophic gastritis in mice
Enhancement of gastric leptin expression in the early period of HFD feeding. a Gene expression of gastric-specific molecules at 1 week after CD and HFD feeding. b Gastric sections stained for leptin in mice fed CD or HFD for 1, 12, and 20 weeks. c Quantification of leptin expression in (b). The data are presented as the relative expression at each time-point to the expression level in the antrum of CD-fed mice after 1 week. d Serum leptin concentration in mice fed CD and HFD for 1 week. The values represent the means ± SD of 5 mice. The results were analyzed by the Mann–Whitney U test. * p < 0.05, ** p < 0.01