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Table 9 Relative gene expressions in liver and heart of apoE−/− mice

From: Dietary intake of cod and scallop reduces atherosclerotic burden in female apolipoprotein E-deficient mice fed a Western-type high fat diet for 13 weeks

Gene Chicken Cod-scallop Gene Chicken Cod-scallop
Liver Heart
Cytokines and chemokines Cytokines and chemokines
Ccl2 1.0 ± 0.11 0.85 ± 0.05 Ccl2 1.0 ± 0.12 0.80 ± 0.10
Il1b 1.0 ± 0.13 0.86 ± 0.05 Ilb1 1.0 ± 0.16 1.20 ± 0.38
Icam1 1.0 ± 0.13 0.97 ± 0.05 Icam1 1.0 ± 0.06 1.03 ± 0.11
Vcam1 1.0 ± 0.06 0.81 ± 0.06* Cardiac function and homeostasis
Endogenous antioxidant system Agtr1 1.0 ± 0.08 1.09 ± 0.13
Pon2 1.0 ± 0.04 0.84 ± 0.04* Ankrd1 1.0 ± 0.13 1.03 ± 0.24
Nfe212 1.0 ± 0.05 0.94 ± 0.04 Nppa 1.0 ± 0.31 1.17 ± 0.43
Sod1 1.0 ± 0.05 1.04 ± 0.07 Nppb 1.0 ± 0.21 1.07 ± 0.34
Sod2 1.0 ± 0.03 1.05 ± 0.03 Myh6 1.0 ± 0.04 1.10 ± 0.08
Gpx1 1.0 ± 0.05 1.01 ± 0.04 Myh7 1.0 ± 0.15 0.80 ± 0.12
Gpx4 1.0 ± 0.04 1.04 ± 0.04 Angiogenesis
Ucp2 1.0 ± 0.13 0.94 ± 0.08 Vegfb 1.0 ± 0.06 1.07 ± 0.15
Cholesterol and lipoprotein metabolism Apoptosis
Abcg5 1.0 ± 0.26 0.89 ± 0.09 Bcl2 1.0 ± 0.07 0.99 ± 0.07
Abcg8 1.0 ± 0.25 0.77 ± 0.07 Casp3 1.0 ± 0.08 1.14 ± 0.14
Acat2 1.0 ± 0.21 0.95 ± 0.05 Fibrosis
ApoB 1.0 ± 0.18 0.98 ± 0.05 Col1A1 1.0 ± 0.06 1.10 ± 0.12
Cyp7a1 1.0 ± 0.26 0.89 ± 0.06 Col3A1 1.0 ± 0.06 1.01 ± 0.09
Hmgcr 1.0 ± 0.08 1.05 ± 0.07 Fn1 1.0 ± 0.04 1.07 ± 0.14
Ldlr 1.0 ± 0.25 0.81 ± 0.05 Timp1 1.0 ± 0.24 0.89 ± 0.15
Srb1 1.0 ± 0.52 0.37 ± 0.02    
Vldr1 1.0 ± 0.20 1.05 ± 0.09    
Nitrogen and fatty acid metabolism    
Cps1 1.0 ± 0.09 1.17 ± 0.08    
Cpt1a 1.0 ± 0.06 0.98 ± 0.06    
Acox1 1.0 ± 0.05 1.05 ± 0.02    
Acaca 1.0 ± 0.17 1.01 ± 0.19    
Scd1 1.0 ± 0.31 1.91 ± 0.30    
Adipoq 1.0 ± 0.58 0.99 ± 0.07    
Adipor 1.0 ± 0.05 0.93 ± 0.02    
Ffar1 1.0 ± 0.11 1.11 ± 0.06    
  1. The mice were fed diets containing different protein sources for 13 weeks. Data are mean ± SEM (n = 10–12)
  2. *Indicate significant difference (p<0.05) between dietary treatments.