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Table 9 Relative gene expressions in liver and heart of apoE−/− mice

From: Dietary intake of cod and scallop reduces atherosclerotic burden in female apolipoprotein E-deficient mice fed a Western-type high fat diet for 13 weeks

Gene

Chicken

Cod-scallop

Gene

Chicken

Cod-scallop

Liver

Heart

Cytokines and chemokines

Cytokines and chemokines

Ccl2

1.0 ± 0.11

0.85 ± 0.05

Ccl2

1.0 ± 0.12

0.80 ± 0.10

Il1b

1.0 ± 0.13

0.86 ± 0.05

Ilb1

1.0 ± 0.16

1.20 ± 0.38

Icam1

1.0 ± 0.13

0.97 ± 0.05

Icam1

1.0 ± 0.06

1.03 ± 0.11

Vcam1

1.0 ± 0.06

0.81 ± 0.06*

Cardiac function and homeostasis

Endogenous antioxidant system

Agtr1

1.0 ± 0.08

1.09 ± 0.13

Pon2

1.0 ± 0.04

0.84 ± 0.04*

Ankrd1

1.0 ± 0.13

1.03 ± 0.24

Nfe212

1.0 ± 0.05

0.94 ± 0.04

Nppa

1.0 ± 0.31

1.17 ± 0.43

Sod1

1.0 ± 0.05

1.04 ± 0.07

Nppb

1.0 ± 0.21

1.07 ± 0.34

Sod2

1.0 ± 0.03

1.05 ± 0.03

Myh6

1.0 ± 0.04

1.10 ± 0.08

Gpx1

1.0 ± 0.05

1.01 ± 0.04

Myh7

1.0 ± 0.15

0.80 ± 0.12

Gpx4

1.0 ± 0.04

1.04 ± 0.04

Angiogenesis

Ucp2

1.0 ± 0.13

0.94 ± 0.08

Vegfb

1.0 ± 0.06

1.07 ± 0.15

Cholesterol and lipoprotein metabolism

Apoptosis

Abcg5

1.0 ± 0.26

0.89 ± 0.09

Bcl2

1.0 ± 0.07

0.99 ± 0.07

Abcg8

1.0 ± 0.25

0.77 ± 0.07

Casp3

1.0 ± 0.08

1.14 ± 0.14

Acat2

1.0 ± 0.21

0.95 ± 0.05

Fibrosis

ApoB

1.0 ± 0.18

0.98 ± 0.05

Col1A1

1.0 ± 0.06

1.10 ± 0.12

Cyp7a1

1.0 ± 0.26

0.89 ± 0.06

Col3A1

1.0 ± 0.06

1.01 ± 0.09

Hmgcr

1.0 ± 0.08

1.05 ± 0.07

Fn1

1.0 ± 0.04

1.07 ± 0.14

Ldlr

1.0 ± 0.25

0.81 ± 0.05

Timp1

1.0 ± 0.24

0.89 ± 0.15

Srb1

1.0 ± 0.52

0.37 ± 0.02

   

Vldr1

1.0 ± 0.20

1.05 ± 0.09

   

Nitrogen and fatty acid metabolism

   

Cps1

1.0 ± 0.09

1.17 ± 0.08

   

Cpt1a

1.0 ± 0.06

0.98 ± 0.06

   

Acox1

1.0 ± 0.05

1.05 ± 0.02

   

Acaca

1.0 ± 0.17

1.01 ± 0.19

   

Scd1

1.0 ± 0.31

1.91 ± 0.30

   

Adipoq

1.0 ± 0.58

0.99 ± 0.07

   

Adipor

1.0 ± 0.05

0.93 ± 0.02

   

Ffar1

1.0 ± 0.11

1.11 ± 0.06

   
  1. The mice were fed diets containing different protein sources for 13 weeks. Data are mean ± SEM (n = 10–12)
  2. *Indicate significant difference (p<0.05) between dietary treatments.