Fig. 1

Weight and glucose tolerance measured during the study. a Weight during the study for the normal diet (ND, ○), normal diet + fructose (HF, ●), high fat diet (HFD, □) and HFD + fructose (HFHF, ■) groups. * Global significant results versus age-matched ND-rats. b Evolution of glycaemia and the area under the curves (AUC) during intraperitoneal glucose tolerance (IpGTT) test on fasting rats (0) and 15, 30, 60, 120 min after glucose injection in all groups and at the beginning (Ctr-rats, M0) and after 2 (M2) and 8 (M8) months of diet. Results are shown as mean ± SEM of 5 different experiments. * Significant results versus age-matched ND-rats