Table 1 List or thermoregulatory or beige markers employed in this study and their function
From: Evaluation of markers of beige adipocytes in white adipose tissue of the mouse
Thermoregulatory or Beige marker | Function |
|---|---|
UCP1 (Uncoupling protein 1) | Uncouples respiration from energy production |
CIDEA (Cell Death-Inducing DFFA-Like Effector A) | Modulates uncoupling action of UCP1 |
Cox8b (Cytochrome C Oxidase Subunit VIIIb) | Subunit of oxidase involved in respiratory electron transport |
FGF21 (Fibroblast Growth Factor 21) | Modulates glucose, lipid, and energy homeostasis: induces beigeing in WAT |
Car4 (Carbonic Anhydrase 4) | Acid–base balance (bicarbonate/CO2 equilibrium) |
P2RX5 (Purinergic Receptor P2X, Ligand-Gated Ion Channel 5) | Purinergic Signaling |
PAT-2 (Proton-Coupled Amino Acid Transporter-2) | Amino acid transport |
CITED1 (Cbp/p300-Interacting Transactivator with Glu/Asp-rich Carboxy-Terminal Domain 1) | Transcriptional coactivator |
CD137/Tnfrs9 (Tumor Necrosis Factor Receptor Superfamily, Member 9) | Inflammatory reactions |
TBX1 (T-Box 1) | Transcription factor (proliferation and differentiation of cells during organogenesis) |
TMEM26 (Transmembrane Protein 26) | Unknown |