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Fig. 9 | Nutrition & Metabolism

Fig. 9

From: The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice

Fig. 9

Expression of inflammation and ER stress related genes in isolated islets from aP2-CETPTg mice. a As for the mRNA level of pro-inflammatory markers, IL-1β was higher in aP2-CETPTg mice than their control, but TNF-α and IL-6 mRNA expression did not differ between the two groups. For the anti-inflammatory marker, IL-10 mRNA level had an increasing tendency in aP2-CETPTg mice. b Relative mRNA levels of CHOP and Xbp1 in isolated islets were increased in aP2-CETPTg mice. n = 4–6 per group. Values are expressed as mean ± SD. *p < 0.05, and *** p < 0.001 compared with control group. Xbp1 X-box binding protein 1, Atf6 activating transcription factor 6

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