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Table 4 Hazard ratio (95 % CI) of coronary heart disease by tertiles of dietary intakes of L-arginine

From: Dietary L-arginine intake and the incidence of coronary heart disease: Tehran lipid and glucose study

  Dietary intakes of L-arginine (n = 1237)
  1st tertile 2nd tertile 3rd tertile 1 SD increased intakes
Total L-arginine (g/d) <3.25 3.25–4.42 ≥4.42  
Adjustment for age and sex Ref. 1.16 (0.59–2.29) 1.33 (0.69–2.59) -
Multivariate model 1 Ref. 1.22 (0.61–2.41) 1.37 (0.68–2.60) -
Multivariate model 2 Ref. 1.23 (0.61–2.43) 1.39 (0.69–2.66) 1.07 (0.63–1.81)
L-arginine from animal sources (g/d) <1.45 1.45–1.78 ≥1.87  
Adjustment for age and sex Ref. 1.87 (1.01–3.48) 1.32 (0.65–2.66) -
Multivariate model 1 Ref. 1.85 (0.99–3.45) 1.29 (0.64–2.60) -
Multivariate model 2 Ref. 1.90 (1.03–3.58) 1.46 (0.72–2.98) 1.12 (0.72–1.73)
L-arginine from plant sources (g/d) <1.85 1.85–2.20 ≥2.20  
Adjustment for age and sex Ref. 1.21 (0.62–2.35) 0.97 (0.50–1.89) -
Multivariate model 1 Ref. 1.20 (0.61–2.38) 0.97 (0.48–1.92)
Multivariate model 2 Ref. 0.91 (0.51–1.62) 0.72 (0.39–1.32) 0.90 (0.51–1.61)
  1. Cox proportional hazard regression models were used
  2. Model 1: Additionally adjusted for BMI (kg/m2) and smoking status (yes/no)
  3. Model 2: Additionally adjusted for hypertension (yes/no) and diabetes mellitus (yes/no)