Fig. 1From: Apple polyphenol extract improves insulin sensitivity in vitro and in vivo in animal models of insulin resistance Acute effects of APE (dose of 150 mg/kg bw) on the postprandial glycemic (a) and insulinemic (c) responses of maltodextrin in OZR and on the respective areas under the curve (b, d). Acute effects of APE (dose of 150 mg/kg bw) on the second-meal effect. Blood glucose (e) and area under the curve (f) after a first load of 150 mg APE/kg b.w. at 8:00 in the morning (simulating breakfast meal) and after a second load 1 g maltodextrin/kg bw (simulating lunch meal) 5 h later. Results are expressed as mean ± SEM, n = 10 in each group. (a) p < 0.05 compared with control groupBack to article page