From: Role of BAF60a/BAF60c in chromatin remodeling and hepatic lipid metabolism
Periportal zone | Perivenous zone | References | ||
---|---|---|---|---|
Metabolic function | Protein | Metabolic function | Protein | |
Lipid metabolism | ||||
Fatty-acid oxidation, Cholesterol synthesis | 3-hydroxyacyl-CoA dehydrogenase, CPI | Lipogenesis | ACC, ACL, FAS, | |
Ketogenesis | β-hydroxybutyrate dehydrogenase, | |||
Bile acid synthesis | ||||
Glucose metabolism | ||||
Gluconeogenesis | G6Pas, FBPas, PEPCK, Lactate dehydrogenase | Glycolysis | GK, PKL | |
Glycogen synthesis | ||||
Alanine aminotransferase | ||||
Ammonia and aminoacid utilization | ||||
Urea synthesis, Aminoacid degradation | CPS1, OTC, ASS, Arg, TAT, SerDH, Alanine aminotransferase | Glutamine synthesis | GS | |
Aspartate aminotranferase | ||||
Xenobiotic metabolism | ||||
 |  | Monooxygenation, Glucuronidation | Cytochrome P450 monooxygenases | |
GST, sulfotransferases |