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Fig. 2 | Nutrition & Metabolism

Fig. 2

From: The effect of interaction between Melanocortin-4 receptor polymorphism and dietary factors on the risk of metabolic syndrome

Fig. 2

Adjusted OR for abdominal obesity to quartile of iron intake by MC4R genotypes (p interaction = 0.002). Q1 < 13.88 mg, Q2 = 13.88–15.98 mg, Q3 = 15.98–40.36 mg, Q4 > 40.36 mg. Among other nutrients (iron, zinc and magnesium), iron has an interaction with this SNP in the development of abdominal obesity (P interaction = 0.006); in A allele carriers, the risk of abdominal obesity did not change significantly with increased iron consumption (P trend = 0.50) but for GG genotype carriers, more consumption of iron led to an increase in risk of abdominal obesity (P trend = 0.002)

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