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Table 1 Characteristics of the study population in subjects with metabolic syndrome (MetS) cases and controls

From: The effect of interaction between Melanocortin-4 receptor polymorphism and dietary factors on the risk of metabolic syndrome

 

Without MetS (n = 815)

With MetS (n = 815)

 

SD

 

SD

Baseline Age (y)†

43.03

12

43.31

11

 Men

44.4

12

41.8

12

 Women

43.7

11

42.9

11

Current smokers (%)

21.7

 

20.7

 

Physical activity (MET.h/w)

7.46

12

7.34

13

Education level ≥14 years (%)

11.9

 

9.5

 

Baseline BMIa (Kg/m2)

24.0

4

28.1*

4

Obesity (%)b

16.0

 

47.2*

 

Baseline WC (cm)

83.2

10

93.2*

11

Abdominal obesity (%)c

54.0

 

90.7*

 

Baseline systolic BP (mmHg)

112.4

15

121.88*

17

Baseline diastolic BP (mmHg)

73.8

8

79.6*

8

Elevated BP (%)d

20.6

 

58.3*

 

Baseline HDL-C (mg/dl)

58.9

9

44.8 *

10

Low HDL-C (%)e

28.7

 

82.6*

 

Baseline TG (mg/dl)

104.5

42

174.1*

71

High TG (%)f

14.0

 

68.0*

 

Baseline FBG (mg/dl)

87.0

12

109.95*

10

High FBG (%)g

21.4

 

79.1*

 

Energy intake (Kcal/day)

2414

1072

2410

878

Carbohydrate (% of energy)

59.1

8

59.4

9

Total fat (% of energy)

30.1

8

29.9

7.2

Saturated fat (% of energy)

10.1

3

9.8

3

MUFA (% of energy)

10.0

3

10.0

2

PUFA (% of energy)

6.0

2

6.1

2

Allele frequency rs12970134 n (%)

 G

1038 (63)

 

989 (60)

 

 A

592 (36)

 

641 (39)

 

Genotype frequency rs12970134 n (%)

 GG

330 (40.5)

 

297 (36.4)

 

 AG

378 (46.6)

 

395 (48.5)

 

 AA

107 (13.1)

 

123 (15.1)

 
  1. BMI body mass index, WC waist circumference, BP blood pressure, HDL-C high density lipoprotein cholesterol, TG triacylglycerol, FBG fasting blood glucose, MUFA mono-unsaturated fatty acids, PUFA poly-unsaturated fatty acids
  2. *P < 0.05; †values are mean unless otherwise listed. abaseline means at first phase or second phase of TLGS. bBMI ≥30 kg/m2, cWC ≥ 95 cm for both genders. dBP ≥130/85 mmHg, eHDL-C <40 mg/dl in men and <50 mg/d in women; fTG ≥ 150 mg/dl, gFBG ≥110 mg/dl