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Table 4 Association between MC4R rs17782313 polymorphism and obesity according to energy and fat intake

From: Interactions with the MC4R rs17782313 variant, mental stress and energy intake and the risk of obesity in Genome Epidemiology Study

  TT CT CC Interactiond
Energy intake Higher than EER 1a 1.022 (1.005–1.039)*,b 1.053 (1.019–1.087)** 0.0594
Lower than EER 1 1.002 (0.945–1.062) 1.064 (0.961–1.177)
Fat intake Higher fat (≥14 %) 1 1.015 (0.989–1.042)b 1.052 (1.003–1.103)* 0.4531
Lower fat (<14 %) 1 1.021 (0.996–1.047) 1.045 (0.994–1.099)
Stress status High stress 1 1.012 (0.983–1.042)c 1.112 (1.054–1.173)*** 0.0359
Low stress 1 1.027 (1.006–1.049)* 1.020 (0.978–1.062)
  1. *Significantly different from reference group at P = 0.05. ** P = 0.01, *** P = 0.001
  2. aReference group
  3. bOdds ratio and 95 % confidence intervals after adjusted for age, gender, residence area, total activity and smoking status
  4. cOdds ratio and 95 % confidence intervals after adjusted for age, gender, residence area, daily energy intake, total activity and smoking status
  5. d P value for the interaction term between MC4R polymorphism and energy intake, fat intake or stress status in the logistic regression model