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Table 2 Interaction of the FTO SNP (rs8050136) with dietary factors on BMI, obesity, waist circumference and Type 2 diabetes

From: Interaction between FTO gene variants and lifestyle factors on metabolic traits in an Asian Indian population

SNP * Fat energy percentage

SNP * Protein energy percentage

SNP * Carbohydrate energy percentage

SNP * energy adjusted glycemic load

SNP * energy adjusted glycemic index

SNP * dietary fibre

Beta coefficients ± standard error (Pinteraction)¥ for interaction on BMI

−0.06 ± 0.06 (0.27)

−0.16 ± 0.23 (0.49)

0.02 ± 0.04 (0.67)

0.002 ± 0.007 (0.81)

0.05 ± 0.09 (0.60)

−0.01 ± 0.02 (0.55)

Beta coefficients ± standard error (Pinteraction)¥ for interaction on obesity

−0.05 ± 0.03 (0.07)

−0.11 ± 0.11(0.29)

0.04 ± 0.02 (0.04)

0.005 ± 0.003 (0.08)

0.05 ± 0.04 (0.21)

−0.008 ± 0.01 (0.45)

Beta coefficients ± standard error (Pinteraction)¥ for interaction on waist circumference

−0.14 ± 0.14 (0.34)

−0.27 ± 0.57 (0.64)

0.04 ± 0.11 (0.68)

0.004 ± 0.02 (0.83)

0.20 ± 0.23 (0.38)

−0.03 ± 0.06 (0.57)

Beta coefficients ± standard error (Pinteraction)** for interaction on Type 2 diabetes

0.01 ± 0.03 (0.73)

−0.03 ± 0.12 (0.78)

0.007 ± 0.02 (0.73)

0.00008 ± 0.003 (0.98)

−0.02 ± 0.05 (0.70)

0.03 ± 0.01 (0.01)

  1. ¥ P values adjusted for age, gender and type 2 diabetes
  2. **P values adjusted for age, gender and obesity