Skip to main content

Table 3 Interaction of the FTO SNP (rs11076023) with dietary factors on BMI, obesity, waist circumference and Type 2 diabetes

From: Interaction between FTO gene variants and lifestyle factors on metabolic traits in an Asian Indian population

SNP * Fat energy percentage

SNP * Protein energy percentage

SNP * Carbohydrate energy percentage

SNP * energy adjusted glycemic load

SNP * energy adjusted glycemic index

SNP * dietary fibre

Beta coefficients ± standard error (Pinteraction)¥ for interaction on BMI

0.009 ± 0.04 (0.79)

0.10 ± 0.14 (0.44)

0.004 ± 0.03 (0.89)

0.003 ± 0.004 (0.52)

0.03 ± 0.06 (0.57)

−0.03 ± 0.01 (0.03)

Beta coefficients ± standard error (Pinteraction)¥ for interaction on obesity

0.0004 ± 0.01 (0.98)

−0.04 ± 0.06 (0.50)

0.004 ± 0.01 (0.74)

0.001 ± 0.002 (0.59)

0.01 ± 0.03 (0.59)

−0.01 ± 0.007 (0.17)

Beta coefficients ± standard error (Pinteraction)¥ for interaction on waist circumference

−0.12 ± 0.0.09 (0.18)

−0.32 ± 0.34 (0.34)

0.11 ± 0.07 (0.12)

0.02 ± 0.01 (0.04)

0.25 ± 0.14 (0.08)

−0.12 ± 0.04 (0.0008)

Beta coefficients ± standard error (Pinteraction)** for interaction on Type 2 diabetes

−0.03 ± 0.02 (0.15)

−0.08 ± 0.07 (0.27)

0.02 ± 0.01 (0.09)

0.003 ± 0.002 (0.16)

0.02 ± 0.03 (0.53)

−0.007 ± 0.007 (0.39)

  1. ¥ P values adjusted for age, gender and type 2 diabetes
  2. **P values adjusted for age, gender and obesity