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Table 6 Hazard ratios of lipid measures for predicting non-cardiovascular mortality among total participants (n = 5518); Tehran Lipid and Glucose Study (TLGS) (2001–2012)a

From: Divergent pathway of lipid profile components for cardiovascular disease and mortality events: Results of over a decade follow-up among Iranian population

 

Model 1

Model 2

SD (mmol/L)

HR (95 % CI)

p-value

HR (95 % CI)

p-value

TC

1.22

0.8(0.70-0.92)

0.001

0.76(0.66-0.87)

<0.001

LDL-C

1.01

0.79(0.69-0.90)

<0.001

0.75(0.66-0.86)

<0.001

HDL-C

0.28

1.08(0.95-1.22)

0.24

1.07(0.94-1.21)

0.32

Non-HDL-C

1.20

0.79(0.69-0.90)

<0.001

0.73(0.64-0.84)

<0.001

ln-TGs

0.32

0.89(0.78-1.0)

0.06

0.81(0.7-0.93)

0.002

TC/HDL-C

1.77

0.81(0.71-0.94)

0.004

0.77(0.67-0.89)

0.001

ln-TGs/HDL-C

0.76

0.89(0.79-1.01)

0.076

0.83(0.72-0.95)

0.006

  1. Model 1: lipid profile + gender; model 2 = model 1 + blood pressure status (i.e. normotension, prehypertension and hypertension status), glucose tolerance status (normal glucose tolerance, prediabetes and diabetes), education status, low physical activity, current smoker, lipid lowering drugs, body mass index and prevalent cardiovascular disease
  2. aHazard ratios indicate the increased risk for a 1-SD increase of each lipid parameter
  3. SD standard deviation, TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, ln-TGs logarithm-transformed triglycerides, CI confidence interval