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Table 7 Crude and multivariate adjusted hazard ratios of non-cardiovascular mortality based on lipid profile tertiles of total participants (n = 5518); Tehran Lipid and Glucose Study (TLGS) (2001–2012)

From: Divergent pathway of lipid profile components for cardiovascular disease and mortality events: Results of over a decade follow-up among Iranian population

  Model 1    Model 2    
Tertiles of variables Tertiles of variables  
1 2 3 1 2 3 P for trend*
TC, mmol/L Reference 0.73(0.55-0.98) (0.61-0.45-0.83) Reference 0.75(0.55-1.01) 0.57(0.42-0.79) 0.001
LDL-C, mmol/L Reference 0.62(0.46-0.83) 0.61(0.45-0.82) Reference 0.64(0.47-0.87) 0.57(0.42-0.77) <0.001
HDL-C, mmol/L Reference 0.86(0.63-1.19) 1.01(0.75-1.34) Reference 0.97(0.7-1.34) 1.07(0.79-1.45) 0.62
Non-HDL-C Reference 0.61(0.45-0.82) 0.63(0.47-0.84) Reference 0.62(0.46-0.84) 0.58(0.43-0.79) <0.001
TGs, mmol/L Reference 0.87(0.66-1.15) 0.71(0.52-0.96) Reference 0.8(0.60-1.08) 0.59(0.42-0.82) 0.002
TC/HDL-C Reference 0.78(0.58-1.03) 0.66(0.49-0.90) Reference 0.77(0.58-1.03) 0.6(0.44-0.83) 0.002
TGs/HDL-C Reference 0.91(0.69-1.21) 0.79(0.58-1.06) Reference 0.82(0.61-1.10) 0.65(0.47-0.91) 0.01
  1. Model 1: lipid profile tertiles + gender; model 2 = model 1 + blood pressure status (i.e. normotension, prehypertension and hypertension status), glucose tolerance status (normal glucose tolerance, prediabetes and diabetes), education status, low physical activity, current smoker, lipid lowering drugs, body mass index and prevalent cardiovascular disease
  2. TC total cholesterol, LDL-C low density lipoprotein cholesterol, HDL-C high density lipoprotein cholesterol, TGs triglycerides, CI confidence interval
  3. *P-values were calculated using age scale Cox proportional hazards regression models