Control | vHS | HF | HFHS | HFvHS | |
---|---|---|---|---|---|
VLDL-C (mM) a | 0.19 (0.11–0.33) | 0.18 (0.11–0.30) | 1.01 (0.60–1.72) ** ### | 0.89 (0.52–1.51) ** ## | 0.68 (0.40–1.16) * # |
LDL-C (mM) a | 1.22 (0.92–1.62) | 1.55 (1.17–2.06) | 9.04 (6.81–12.0) **** #### | 7.86 (5.90–10.4) **** #### | 6.54 (4.93–8.68) **** #### |
HDL-C (mM) a | 0.04 (0.03–0.06) | 0.04 (0.03–0.06) | 0.07 (0.04–0.10) | 0.10 (0.06–0.15) | 0.09 (0.06–0.15) |
FFA (mM) | 0.77 ± 0.23 | 0.68 ± 0.16 | 0.50 ± 0.15 | 0.51 ± 0.09 | 0.52 ± 0.21 |
SAA (μg/mL) a | 89.4 (47.5–168) | 182 (91.8–359) | 14.3 (7.22–28.3) ** #### | 22.5 (10.7–47.5) ## | 10.8 (5.77–20.4) *** #### |
% Liver weight a | 2.16 (1.92–2.43) | 2.29 (2.03–2.57) | 4.72 (4.19–5.31) **** #### | 4.63 (4.11–5.21) **** #### | 4.30 (3.82–4.84) **** #### |
ALT (U/L) a | 43.1 (34.1–54.7) | 32.4 (25.6–41.1) | 92.5 (73.0–117) *** #### | 106 (83.8–128) **** #### | 98.1 (76.0–127)*** #### |
AST (U/L) a | 67.0 (47.3–95.2) | 51.5 (36.3–73.1) | 403 (284–572) **** #### | 450 (317–639) **** #### | 323 (221–471) **** #### |
ALP (U/L) | 70.3 ± 5.53 | 60.7 ± 18.5 | 59.0 ± 14.6 | 53.9 ± 9.19 | 51.9 ± 17.3 |