Control | vHS | HF | HFHS | HFvHS | |
---|---|---|---|---|---|
VLDL-C (mM) a | 0.12 (0.07–0.20) | 0.13 (0.08–0.23) | 1.02 (0.60–1.74) **** #### | 1.38 (0.81–2.35) **** #### | 0.89 (0.52–1.51) **** ### |
LDL-C (mM) a | 0.99 (0.74–1.31) | 1.15 (0.87–1.52) | 7.74 (5.83–10.3) **** #### | 7.83 (5.90–10.4) **** #### | 7.38 (5.56–9.79) **** #### |
HDL-C (mM) a | 0.03 (0.02–0.05) | 0.04 (0.02–0.06) | 0.06 (0.04–0.10) | 0.08 (0.05–0.12) | 0.07 (0.04–0.10) |
FFA (mM) | 0.48 ± 0.22 | 0.61 ± 0.12 | 0.58 ± 0.13 | 0.64 ± 0.13 | 0.43 ± 0.17 |
SAA (μg/mL) a | 46.6 (24.8–87.7) | 88.3 (46.9–166) | 20.9 (10.6–41.3) | 48.1 (24.3–95.2) | 12.3 (6.56–23.2) ## |
% Liver weight a | 2.07 (1.84–2.32) | 2.55 (2.27–2.87) | 4.90 (4.35–5.51) **** #### | 5.19 (4.61–5.84) **** #### | 4.97 (4.42–5.59)**** #### |
ALT (U/L) a | 37.0 (29.2–46.9) | 30.2 (23.8–38.2) | 77.7 (61.3–98.3) ** #### | 101 (79.7–128) **** #### | 86.4 (68.3–109) *** #### |
AST (U/L) a | 43.6 (30.7–61.8) | 43.7 (30.8–62.0) | 259 (183–368) **** #### | 428 (302–607) **** #### | 445 (314–631) **** #### |
ALP (U/L) | 60.1 ± 4.88 | 59.6 ± 13.1 | 45.9 ± 5.18 | 43.3 ± 1.70 | 47.0 ± 7.05 |