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Table 2 Differential expression of genes in h-MSC-derived adipocytes exposed to PhIP

From: 2-amino-1-methyl-6-phenylimidazo(4,5-b) pyridine (PhIP) induces gene expression changes in JAK/STAT and MAPK pathways related to inflammation, diabetes and cancer

Gene Symbol Accession Ave Expression FC P.Value adj.P.Val
ANGPTL2a NM_012098.2 8.578 1.88 6.19E-07 0.59E-04
EGR1a NM_001964.2 8.750 -2.93 2.65E-10 1.25E-05
FOSa NM_005252.2 7.120 -1.95 2.57E-08 0.61E-05
IBP5a NM_000599.2 8.550 1.91 2.45E-06 0.014
CIDEA NM_001279.2 6.697 1.49 3.24E-07 0.39E-04
PALM NM_002579.2 8.575 1.63 4.06E-06 0.018
PSAT1 NM_021154.3 8.614 -1.62 4.26E-06 0.018
CD14 NM_001040021.1 7.650 1.58 1.93E-05 0.05
  1. Differentially expressed genes in hMSC derived adipocyte exposed to 5 nM PhiP for 72 h, adjusted for multiple comparisons, significant at the p = 0.05 level
  2. aReceptor ligands, transcriptional factors and/or binding proteins that are significant and are controlled by the STAT3 transcriptional factor in the gene-gene interaction and pathway analyses (see Figs. 4 and 5)