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Table 1 Some clinical and laboratory data of both studied groups

From: Assessment of Vitamin D status in a group of Egyptian children with non alcoholic fatty liver disease (multicenter study)

Parameter

 

NAFLD patients

Controls

P- value

  

(No = 47)

(No = 23)

 

Age

Mean ± SD

11.13 ± 2.7

10.6 ± 3.1

0.43

Sex

Male (%)

19 (40.4 %)

9 (39.1 %)

0.32

 

Female (%)

28 (59.6 %)

14 (60.9 %)

 

BMI centile (th)

Mean ± SD

96.8723 ± 0.5

92.2 ± 9.3

<0.001*

ALT (U/L)

Mean ± SD

63.8 ± 31.1

27.6 ± 5.7

<0.001*

AST (U/L)

Mean ± SD

58.8 ± 22.9

28.8 ± 8.7

<0.001*

GGT (U/L)

Mean ± SD

53.8 ± 21.6

34.5 ± 9.4

<0.001*

Serum albumin (mg/dl)

Mean ± SD

3.5 ± 0.52

3.9 ± 0.2

<0.001*

Total bilirubin (mg/dl)

Mean ± SD

1.4 ± 0.71

0.71 ± 0.2

<0.001*

Direct bilirubin (mg/dl)

Mean ± SD

0.32 ± 0.2

0.14 ± 0.05

<0.001*

Alkaline phosphatase (U/L)

Mean ± SD

214.4 ± 56.6

186.2 ± 46.4

0.01*

CRP (mg/dl)

Mean ± SD

56 ± 18.1

5 ± 3.1

<0.001*

Serum creatinine (mg/dl)

Mean ± SD

0.81 ± 0.35

1 ± 0.19

<0.001*

Serum cholesterol (mg/dl)

Mean ± SD

198.3 ± 27.1

163.8 ± 27.5

<0.001*

Serum triglyceride (mg/dl)

Mean ± SD

191.3 ± 37.6

157.7 ± 32.9

<0.001*

Serum LDL (mg/dl)

Mean ± SD

104.7 ± 36.2

108.13 ± 11.1

0.52

Serum HDL (mg/dl)

Mean ± SD

37.3 ± 9.7

43.4 ± 8.1

0.002*

Fasting Blood glucose (mg/dl)

Mean ± SD

143.3 ± 33.9

100.17 ± 14.7

<0.001*

Fasting insulin (mU/ml)

Mean ± SD

11.7 ± 4.8

4.5 ± 2.9

<0.001*

HOMA-IR

Mean ± SD

76.6 ± 41.4

20.7 ± 16.3

<0.001

Serum 25(OH) D (nmol/L)

Mean ± SD

52.1 ± 41.3

104.7 ± 36.2

<0.001*

  1. *Significant (p value <0.05), BMI body mass index, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT gamma glutamyl transferase, CRP C reactive protein, LDL Low density lipoprotein, HDL High density lipoprotein, HOMA-IR homeostasis model assessment index for insulin resistance and 25(OH)D 25 hydroxy vitamin D