Table 2 Independent samples t-tests comparing time-corrected paraxanthine/caffeine ratios by age, body mass index, caffeine intake, contraceptive pill, CYP1A2 inducibility, gender, insulin administration, long-term medication, smoking status
From: Assessment of CYP1A2 enzyme activity in relation to type-2 diabetes and habitual caffeine intake
Group | N | Time-corrected paraxanthine/caffeine ratio | p value | |
|---|---|---|---|---|
Age | ≤59.3 years | 77 | 0.604 (±0.364) | 0.290 |
>59.3 years | 126 | 0.561 (±0.438) | ||
BMI | ≤24.9 kg/m2 | 117 | 0.560 (±0.415) | 0.580 |
>24.9 kg/m2 | 84 | 0.603 (±0.408) | ||
Caffeine Intake | ≤288 mg/day | 139 | 0.535 (±0.431) | 0.010 |
>288 mg/day | 64 | 0.669 (±0.350) | ||
Contraceptive Pill | No | 194 | 0.579 (±0.417) | 0.979 |
Yes | 9 | 0.545 (±0.282) | ||
CYP1A2 Inducibility | Less (C/A and C/C genotypes) | 103 | 0.552 (±0.430) | 0.284 |
High (A/A genotype) | 97 | 0.609 (±0.394) | ||
Gender | Male | 87 | 0.631 (±0.467) | 0.237 |
Female | 116 | 0.537 (±0.360) | ||
Insulin Administration | No | 184 | 0.557 (±0.414) | 0.016 |
Yes | 19 | 0.770 (±0.336) | ||
Medication | No | 74 | 0.510 (±0.311) | 0.187 |
Yes | 129 | 0.616 (±0.456) | ||
Smoking Status | Non Smoking | 182 | 0.573 (±0.410) | 0.896 |
Smoking | 21 | 0.617 (±0.430) |