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Table 1 Hardy-Weinberg equilibrium for ACE I/D genotypes

From: Angiotensin-converting enzyme insertion/deletion polymorphism association with obesity and some related disorders in Egyptian females: a case-control observational study

Groupings (n)

Observed frequencies

Expected frequencies

χ 2

p

DD

ID

II

DD

ID

II

All 80 subjects

50

25

5

48.8

27.3

3.8

0.590

0.443

OH (28)

19

7

2

18.1

8.8

1.1

1.212

0.271

ON (23)

14

7

2

13.3

8.4

1.3

0.616

0.433

LH (12)

9

3

0

9.2

2.6

0.2

0.245

0.621

LN (17)

8

8

1

8.5

7.1

1.5

0.302

0.583

Hypertensive (40)

28

10

2

27.2

11.6

1.2

0.720

0.396

Normotensive (40)

22

15

3

21.8

15.5

2.8

0.040

0.842

High BMI (51)

33

14

4

31.4

17.3

2.4

1.915

0.178

Normal BMI (29)

17

11

1

17.5

10.1

1.5

0.238

0.686

High WC (57)

37

16

4

35.5

18.9

2.5

1.379

0.240

Normal WC (23)

13

9

1

13.3

8.4

1.3

0.130

0.718

High WHR (55)

37

15

3

36.0

17.0

2.0

0.755

0.385

Normal WHR (25)

13

10

2

13.0

10.1

2.0

0.002

0.968

High WHtR (69)

43

21

5

41.5

24.0

3.5

1.101

0.294

Normal WHtR (11)

7

4

0

7.4

3.3

0.4

0.543

0.461

High C-index (44)

32

10

2

31.1

11.8

1.1

0.998

0.318

Normal C-index (36)

18

15

3

18.1

14.9

3.1

0.003

0.959

Insulin Resistant (62)

39

21

2

39.5

20.0

2.5

0.168

0.681

Insulin Sensitive (18)

11

4

3

9.4

7.2

1.4

3.583

0.058

MetS (45)

27

15

3

26.5

16.1

2.5

0.210

0.647

No MetS (35)

23

10

2

22.4

11.2

1.4

0.402

0.526

  1. OH obese hypertensive, ON obese normotensive, LH lean hypertensive, LN lean normotensive, BMI body mass index, WC waist circumference, WHR waist/hip ratio, WHtR waist/height ratio, C-index conicity index, MetS metabolic syndrome, DD homozygous deletion genotype, ID heterozygous insertion deletion genotype, II homozygous insertion genotype, χ 2: chi-square test statistic