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Table 2 Glycemic and hormonal responses to an OGTT are similar after pretreatment with sucralose

From: Hormonal responses to non-nutritive sweeteners in water and diet soda

Variable 0 mg sucralose (mean ± SD) 68 mg sucralose (mean ± SD) 170 mg sucralose (mean ± SD) 250 mg sucralose (mean ± SD)
Active GLP-1 AUC (pmol/L/120 min) 1268.4 ± 936.9 1217.7 ± 960.2 1327.4 ± 857.7 1328.4 ± 953.2
Active GLP-1 Peak (pmol/L) 18.2 ± 12.9 16.3 ± 11.1 17.4 ± 10.5 18.5 ± 14.4
GIP AUC (pg/mL/120 min) 13478.2 ± 6328.9 13298.0 ± 5877.8 13646.9 ± 6351.8 13881.6 ± 6720.2
GIP Peak (pg/mL) 139.9 ± 68.3 145.8 ± 80.2 141.0 ± 72.0 143.7 ± 68.2
Glucose AUC (mmol/L/120 min) 750.1 ± 149.2 766.6 ± 148.1 744.8 ± 134.6 730.8 ± 130.7
Glucose Peak (mmol/L) 7.1 ± 1.6 7.3 ± 1.5 7.1 ± 1.4 7.0 ± 1.3
Insulin AUC (pmol/L/120 min) 38571.6 ± 13814.6 39984.9 ± 24316.9 37749.1 ± 16896.9 36437.9 ± 13553.3
Insulin Peak (pmol/L) 420.1 ± 185.6 414.6 ± 182.5 404.1 ± 196.4 374.2 ± 147.8
C-Peptide AUC (nmol/L/120 min) 274.7 ± 71.8 278.3 ± 70.1 272.3 ± 84.1 269.7 ± 614.7
C-Peptide Peak (nmol/L) 3.0 ± 0.8 3.2 ± 0.8 3.1 ± 1.1 3.0 ± 0.8