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Fig. 5 | Nutrition & Metabolism

Fig. 5

From: Dietary selenium augments sarcoplasmic calcium release and mechanical performance in mice

Fig. 5

Depolarization evoked ∆[Ca2+]i and release flux were higher in FDB fibers of selenium treated mice. Line-scan images of fluorescence intensity changes evoked by single depolarization (a) in FDB of control (left), 0.5 ppm NanoSe (middle) and 0.5 ppm selenate (right) feed mice. Intracellular calcium concentration changes (b) calculated from the Ca2+ transient in panel (a). The corresponding calcium release flux through the RyR (c) calculated from the curves in panel (b). The averages of the change in intracellular calcium concentration (d), the total calcium released into the myoplasm (e), and the corresponding calcium release flux (f). ** and *** show significant difference from control at levels of P < 0.01 and P < 0.001, respectively. Numbers in parenthesis give the number of fibers investigated. Measurement conditions: 8000x50 pixel, 0.5 μs/line, 0.66 μm/pixel at room temperature (24 °C)

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