Skip to main content

Advertisement

Table 1 Baseline characteristics of study participants after a 10-h overnight fast

From: Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility

  Lean subjects Obese subjects P Adjusted P *
Age (years) 23.2 ± 0.2 28.6 ± 1.4 0.002  
BMI (kg/m2) 22.0 ± 0.2 30.2 ± 0.8 <0.001 <0.001
Waist Circumference (cm) 79.9 ± 0.5 100.8 ± 1.0 <0.001 <0.001
Fasting Blood Glucose (mmol/l) 4.33 ± 0.05 4.68 ± 0.12 0.026 0.459
Fasting Serum Insulin (mU/l) 4.31 ± 0.52 21.04 ± 2.27 <0.001 <0.001
Fasting Total Cholesterol (mmol/l) 5.09 ± 0.27 5.28 ± 0.40 0.697 0.791
Fasting LDL-Cholesterol (mmol/l) 3.09 ± 0.29 3.20 ± 0.35 0.823 0.730
Fasting HDL-Cholesterol (mmol/l) 1.71 ± 0.08 1.19 ± 0.06 0.001 0.005
Fasting Triglyceride (mmol/l) 0.62 ± 0.07 1.98 ± 0.24 <0.001 0.007
Fasting NEFA (mmol/l)a 0.41 ± 0.04 0.49 ± 0.03 0.037 0.392
HOMA-IR 0.83 ± 0.10 4.34 ± 0.41 <0.001 <0.001
Fasting RQ 0.79 ± 0.01 0.78 ± 0.01 0.784 0.463
  1. Data are presented as the means ± SEM; * age-adjusted, alog transformed comparison of the mean; BMI body mass index, LDL low-density lipoprotein, HDL high-density lipoprotein, HOMA-IR homeostasis model assessment for insulin resistance, NEFA nonesterified fatty acids, RQ respiratory quotient