Metabolic gene expression profile in circulating mononuclear cells reflects obesity-associated metabolic inflexibility

Table 2 Postprandial serum insulin, glucose, triglyceride, and NEFA responses to the test meals

		HC meal	P	HF meal	P
Insulin iAUC_{0-360 min} (mU. min. L^-1)	Obese	20540 ± 2575	0.001	10508 ± 1846	0.019
Insulin iAUC_{0-360 min} (mU. min. L^-1)	Lean	8374 ± 867	0.001	5378 ± 703	0.019
Glucose iAUC_{0-360 min} (mmol. min. L^-1)	Obese	257 ± 40	0.376	147 ± 9	0.685
Glucose iAUC_{0-360 min} (mmol. min. L^-1)	Lean	207 ± 37	0.376	161 ± 32	0.685
Triglyceride iAUC_{0-360 min} (mmol. min. L^-1)	Obese	204.0 ± 59.3	0.067	373.3 ± 77.7	0.004
Triglyceride iAUC_{0-360 min} (mmol. min. L^-1)	Lean	79.0 ± 23.0	0.067	104.9 ± 16.2	0.004
NEFA iAUC_{0-360 min} (mmol. min. L^-1)	Obese	-59.33 ± 13.66	0.969	-28.90 ± 20.27	0.874
NEFA iAUC_{0-360 min} (mmol. min. L^-1)	Lean	-58.40 ± 19.26	0.969	-33.30 ± 18.32	0.874

Data are presented as the mean incremental area under the curve ± SEM; n = 9 for each group. HC high-carbohydrate, HF high-fat; Statistical differences are based on repeated-measures ANOVA

ISSN: 1743-7075