| Placebo (n = 73) | Anthocyanins (n = 73) | P-valueb | ||||||
---|---|---|---|---|---|---|---|---|---|
Baseline | 12 wk | 24 wk | Mean change,% (95% CI)a | Baseline | 12 wk | 24 wk | Mean change,% (95% CI)a | ||
CXCL7 (ng/ml) | 167.63 ± 38.78 | 165.82 ± 37.83 | 166.20 ± 31.92 | 4.22 | 170.52 ± 44.86 | 157.76 ± 43.21 | 138.83 ± 30.49c | −12.32 | 0.011 |
(−2.33 to 11.05) | (−19.25 to −5.00)d | ||||||||
CXCL5 (pg/ml) | 159.43 ± 29.35 | 157.85 ± 31.80 | 157.32 ± 29.74 | 1.93 | 160.40 ± 36.26 | 150.78 ± 28.98 c | 137.61 ± 26.14c | −9.95 | 0.006 |
(−4.18 to 9.28) | (−15.84 to −3.56)d | ||||||||
CXCL8 (pg/ml) | 22.97 ± 2.73 | 22.91 ± 2.51 | 22.97 ± 4.24 | 0.66 | 22.93 ± 1.96 | 22.32 ± 1.61 c | 21.40 ± 1.07c | −6.07 | 0.016 |
(−2.99 to 4.88) | (−8.15 to −4.23)d | ||||||||
CXCL12 (ng/mL) | 2.16 ± 0.53 | 2.15 ± 0.51 | 2.14 ± 0.46 | 5.43 | 2.19 ± 0.56 | 2.11 ± 0.34 | 1.86 ± 0.47c | −8.11 | 0.020 |
(−2.03 to 14.16) | (−15.98 to −0.30)d | ||||||||
CCL2 (pg/mL) | 504.99 ± 165.34 | 502.68 ± 157.33 | 515.76 ± 132.04 | 12.84 | 502.97 ± 139.91 | 476.96 ± 113.74 | 414.61 ± 87.14c | −11.63 | 0.014 |
(1.05 to 27.23) | (−18.16 to −4.85)d | ||||||||
CXCL4L1 (pg/ml) | 124.29 ± 88.87 | 134.00 ± 69.82 | 135.16 ± 75.07 | 0.08 | 126.52 ± 67.05 | 126.44 ± 75.21 | 112.27 ± 86.78 | −0.80 | 0.769 |
(−0.21 to 0.35) | (−2.07 to 0.06) | ||||||||
CXCL1 (ng/ml) | 20.96 ± 3.15 | 21.94 ± 2.38 | 22.92 ± 3.67 | 0.07 | 21.30 ± 4.71 | 21.00 ± 3.37 | 21.07 ± 1.79 | −0.02 | 0.529 |
(−0.06 to 0.19) | (−0.24 to 0.16) | ||||||||
PAI-1 (ng/ml) | 101.52 ± 41.81 | 106.13 ± 48.55 | 108.84 ± 14.31 | 0.08 | 104.07 ± 52.84 | 107.16 ± 36.38 | 99.62 ± 42.35 | −0.44 | 0.888 |
(−0.10 to 0.29) | (−1.34 to 0.20) | ||||||||
MIF (ng/ml) | 32.91 ± 10.02 | 30.46 ± 9.54 | 29.51 ± 14.58 | −9.90 | 32.69 ± 13.94 | 31.26 ± 8.53 | 26.93 ± 10.56 | 2.65 | 0.801 |
(−25.96 to 7.13) | (−32.90 to 39.14) |