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Fig 3 | Nutrition & Metabolism

Fig 3

From: Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosis

Fig 3

Effect of α-MG treatment on : a caspases 9 and 3 activities, b mitochondria membrane expressed as JC-1 fluorescence, d OXPHOS expressed as oxygen consumption rate in FFA-treated hepatocytes. The primary liver cells were treated with α-MG (10, 20, 30 μM) for 24 h. OXPHOS was quantified by seahorse XFe24 Analyzer. Caspases 9 and caspases 3 were quantified by Elisa assays. (*P < 0.05 versus primary liver cells ; # P < 0.05 versus FFA-treated hepatocytes). Values are means ± SD, n = 3. Effect of mangosteen pericarp extract on mitochondrion complex enzymes (NCCR, SCCR) c. OXPHOS: oxidative phosphorylation. NCCR: NADH-cytochrome c reductase. SCCR: succinate-cytochrome c reductase. Values are mean ± SD (n = 8); (*P < 0.05 versus control; # P < 0.05 versus HFD)

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