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Table 1 Physiological parameters in Control (male n = 10, female n = 14) and GK (male n = 13, female n = 12) rats

From: Reduced up-regulation of the nitric oxide pathway and impaired endothelial and smooth muscle functions in the female type 2 diabetic goto-kakizaki rat heart

  Control GK
Male Female Male Female
Plasma glucose mM 10.7 ± 0.3 10.0 ± 0.3 17.9 ± 0.6* 16.9 ± 0.4*
Plasma FFAs mM 0.27 ± 0.03 0.27 ± 0.05 0.28 ± 0.04 0.26 ± 0.04
Body weight g 512 ± 13 265 ± 7 411 ± 4* 270 ± 5
Heart weight g 1.52 ± 0.03 0.88 ± 0.04 1.51 ± 0.02 1.12 ± 0.03*
Ratio Heart/Body weight *1000 2.98 ± 0.05 3.34 ± 0.14 3.66 ± 0.02* 4.17 ± 0.08*
  1. *versus respective Controls, p < 0.0001. versus Male Control, p < 0.05. versus Male GK, p < 0.0001