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Table 4 Endothelium-dependent and independent vasodilatations in Control (male n = 9, female n = 10) and GK (male n = 9, female n = 11) rat hearts

From: Reduced up-regulation of the nitric oxide pathway and impaired endothelial and smooth muscle functions in the female type 2 diabetic goto-kakizaki rat heart

  Control GK
Male Female Male Female
5-HT % 32.6 ± 3.0 33.9 ± 3.3 30.5 ± 2.1 19.9 ± 2.6*
Papaverine % 28.0 ± 3.7 29.4 ± 3.2 32.3 ± 4.4 19.2 ± 2.5*
  1. *p < 0.05 versus Male GK rat hearts. p < 0.05 versus Female Control rat hearts