Hepatic iron storage is related to body adiposity and hepatic inflammation

Nutrition & Metabolism

Table 1 Body weight and weight gain of mice in the CR, Control, and HFD groups¹

	CR (n =16)	Control (n = 24)	HFD (n = 25)	P value
Body weight at 0 week (g)	22.68 ± 0.20	22.40 ± 0.22	22.26 ± 0.21	0.44
Body weight at 16 week (g)	27.53 ± 0.76^a	37.08 ± 0.56^b	48.80 ± 0.49^c	<0.001
Body weight gain (g)	4.8 ± 0.8^a	14.7 ± 0.5^b	26.5 ± 0.5^c	<0.001
Daily calorie intake (kcal/day)	11.43 ± 0.16^a	13.49 ± 0.14^b	15.59 ± 0.15^c	<0.001
White adipose tissue (g) ²	1.76 ± 0.14^a	3.94 ± 0.15^b	6.87 ± 0.11^c	<0.001
Liver weight per body weight (g/100 g body weight)	4.18 ± 0.15^a	5.11 ± 0.11^b	5.58 ± 0.23^b	<0.001

¹One-way ANOVA followed by Fisher’s LSD multiple comparison was used to determine significant differences
²White adipose tissue weight included epididymal, subcutaneous, retroperitoneum, and perinephric fat
^abcDifferent superscript letters indicate significant differences at P < 0.05

ISSN: 1743-7075