Fig. 1

Analysis of serum 25-OH vitamin D₃ concentrations of lean and obese mice in response to altered vitamin D₃ supplementation. Serum 25-OH vitamin D₃ concentration was measured every two weeks using ELISA in lean (L) and obese (O) mice given low (125 IU/kg chow), standard (STD, 1000 IU/kg chow) or high (4000 IU/kg chow) amounts of vitamin D₃ a Decline from baseline serum 25-OH vitamin D concentration was further calculated for L-LOW and O-LOW b. Symbols indicate p < 0.05 between L-HIGH and L-STD (*), L-HIGH and O-HIGH (‡), and L-LOW and O-LOW (†)