Fig. 4
Impacts on bone mineral density and relationship with serum biomarkers. The effects of high fat and low fat diet containing varying levels of vitamin D on bone mineral density were analyzed using DEXA a No statistical differences observed between vitamin D groups. Differences between all lean and obese mice were significant for bone mineral density (a p = 0.004; b p < 0.0001; c p < 0.008). Bone mineral density was not correlated with serum 25-OH b or 1,25-(OH)2 vitamin D c, but was correlated with serum intact PTH (R2 = 0.32, ****p < 0.0001) d