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Table 1 Fasting plasma metabolic parameters

From: Eicosapentaenoic acid shows anti-inflammatory effect via GPR120 in 3T3-L1 adipocytes and attenuates adipose tissue inflammation in diet-induced obese mice

  chow diet (n = 10) HFHS diet (n = 13) HFHS diet + EPA (n = 8)
TC (mg/dL) 67 ± 3.1 181 ± 14* 81 ± 9.6#
TG (mg/dL) 28 ± 3.7 13 ± 1.6* 12 ± 2.0
HDL-C (mg/dL) 38 ± 2.1 63 ± 3.9* 50 ± 5.5
NEFA (μEq/L) 884 ± 99 630 ± 47* 625 ± 79
ALT (IU/L) 9.4 ± 1.9 122 ± 23* 32 ± 11#
Plasma glucose (mg/dL) 106 ± 9 126 ± 4* 79 ± 5#
Insulin (ng/mL) 1.58 ± 0.02 7.06 ± 0.41* 4.15 ± 0.83#
HbAc (%) 4.58 ± 0.05 4.51 ± 0.05 4.52 ± 0.05
  1. Data are expressed as means ± SEM. TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, NEFA nonesterified fatty acid, ALT alanine aminotransferase, HbA1c glycated hemoglobin, HFHS high-fat/high-sucrose, EPA eicosapentaenoic acid * P < 0.05 vs. chow diet, # P < 0.05 vs. HFHS diet