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Table 5 Within-subject correlations of bone biomarkers and inflammatory markersa

From: The role of a dairy fraction rich in milk fat globule membrane in the suppression of postprandial inflammatory markers and bone turnover in obese and overweight adults: an exploratory study

Inflammatory variable C1CP correlation coefficient p-value CTX correlation coefficient p-value
IL-6 −0.20 0.045 −0.08 0.421
IL-18 −0.09 0.338 −0.12 0.202
TNF-α −0.15 0.118 0.05 0.613
CRP 0.14 0.159 0.08 0.445
IL-10 0.02 0.877 −0.10 0.307
sICAM 0.03 0.748 0.01 0.935
  1. aCorrelations calculated for incremental area under the transformed curve, controlling for hour 0 values of the two variables. Correlation coefficients were calculated as partial Pearson correlations; mixed model regression (with a random effect of subject) was used to calculate p-values for each correlation in order to account for the fact that the four measurements were not independent of each other. N = 36
  2. Bone variables: type 1 C-terminal collagen propeptide (C1CP), C-telopeptide of type 1 collagen (CTX)
  3. Inflammatory variables: interleukin-6 (IL-6), interleukin-18 (IL-18), tumor necrosis factor alpha (TNFα), C-reactive protein (CRP), interleukin-10 (IL-10), soluble intercellular adhesion molecule (sICAM)
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