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Table 5 Within-subject correlations of bone biomarkers and inflammatory markersa

From: The role of a dairy fraction rich in milk fat globule membrane in the suppression of postprandial inflammatory markers and bone turnover in obese and overweight adults: an exploratory study

Inflammatory variable

C1CP correlation coefficient

p-value

CTX correlation coefficient

p-value

IL-6

−0.20

0.045

−0.08

0.421

IL-18

−0.09

0.338

−0.12

0.202

TNF-α

−0.15

0.118

0.05

0.613

CRP

0.14

0.159

0.08

0.445

IL-10

0.02

0.877

−0.10

0.307

sICAM

0.03

0.748

0.01

0.935

  1. aCorrelations calculated for incremental area under the transformed curve, controlling for hour 0 values of the two variables. Correlation coefficients were calculated as partial Pearson correlations; mixed model regression (with a random effect of subject) was used to calculate p-values for each correlation in order to account for the fact that the four measurements were not independent of each other. N = 36
  2. Bone variables: type 1 C-terminal collagen propeptide (C1CP), C-telopeptide of type 1 collagen (CTX)
  3. Inflammatory variables: interleukin-6 (IL-6), interleukin-18 (IL-18), tumor necrosis factor alpha (TNFα), C-reactive protein (CRP), interleukin-10 (IL-10), soluble intercellular adhesion molecule (sICAM)