|
Inflammatory variable
|
C1CP correlation coefficient
|
p-value
|
CTX correlation coefficient
|
p-value
|
|---|
|
IL-6
|
−0.20
|
0.045
|
−0.08
|
0.421
|
|
IL-18
|
−0.09
|
0.338
|
−0.12
|
0.202
|
|
TNF-α
|
−0.15
|
0.118
|
0.05
|
0.613
|
|
CRP
|
0.14
|
0.159
|
0.08
|
0.445
|
|
IL-10
|
0.02
|
0.877
|
−0.10
|
0.307
|
|
sICAM
|
0.03
|
0.748
|
0.01
|
0.935
|
-
aCorrelations calculated for incremental area under the transformed curve, controlling for hour 0 values of the two variables. Correlation coefficients were calculated as partial Pearson correlations; mixed model regression (with a random effect of subject) was used to calculate p-values for each correlation in order to account for the fact that the four measurements were not independent of each other. N = 36
- Bone variables: type 1 C-terminal collagen propeptide (C1CP), C-telopeptide of type 1 collagen (CTX)
- Inflammatory variables: interleukin-6 (IL-6), interleukin-18 (IL-18), tumor necrosis factor alpha (TNFα), C-reactive protein (CRP), interleukin-10 (IL-10), soluble intercellular adhesion molecule (sICAM)
