Table 1 Subjects’ characteristics
Variable | Lean (n = 44) | Overweight/obese (n = 73) | P value |
|---|---|---|---|
Age (years) | 51.75 ± 13.8 | 47.89 ± 9.8 | 0.08 |
Male/female | 21(47.73%)/23 | 48(65.75%)/25 | 0.055 |
T2DM history | 28(63.64%) | 48(65.75%) | 0.816 |
Current smoker (%) | 9(20.45%) | 26(35.62%) | 0.083 |
Alcohol use (%) | 14(31.82%) | 31(42.47%) | 0.252 |
Waist-to-hip ratio | 0.9 ± 0.04 | 0.9 ± 0.05 | 0.491 |
Systolic blood pressure (mmHg) | 127.36 ± 17.73 | 132.05 ± 16.73 | 0.154 |
Diastolic blood pressure (mmHg) | 82.59 ± 9.43 | 87.68 ± 9.02 | 0.004** |
Total cholesterol (mmol/L) | 5.06 ± 1.01 | 5.36 ± 1.16 | 0.155 |
Triglycerides (mmol/L) | 1.69 ± 1.41 | 2.55 ± 2.24 | 0.025* |
High-density lipoprotein (mmol/L) | 1.33 ± 0.29 | 1.26 ± 0.27 | 0.157 |
Low-density lipoprotein (mmol/L) | 3.07 ± 0.84 | 3.2 ± 0.81 | 0.407 |
Fasting plasma glucose (mmol/L) | 7.28 ± 3.29 | 8.18 ± 3.7 | 0.186 |
Fasting serum insulin (mmol/L) | 8.46 ± 5.92 | 13.44 ± 8.70 | 0.001** |
HOMA-IR (μIU x mol/L) | 3.02 ± 3.94 | 5.42 ± 5.19 | 0.009** |
Hemoglobin A1c (%) | 6.94 ± 2.32 | 7.54 ± 2.28 | 0.173 |
Musclin(ng/L) | 80.39 ± 16.35 | 89.49 ± 19.00 | 0.009** |