Positive association between musclin and insulin resistance in obesity: evidence of a human study and an animal experiment

Table 4 Comparison of plasma biochemical indicators in HFD and ND rats

Parameters	ND	HFD
Body weight (g)	546.30 ± 16.29	620.01 ± 13.31^**
Lee index	301.27 ± 1.73	315.97 ± 2.26^**
Fat mass/body weight (%)	4.12 ± 0.29	7.80 ± 0.72^**
Triglyceride (mmol/L)	0.72 ± 0.04	0.92 ± 0.05^*
Total cholesterol (mmol/L)	2.42 ± 0.10	3.02 ± 0.19^*
High-density lipoprotein (mmol/L)	1.08 ± 0.10	0.51 ± 0.03^**
Low-density lipoprotein (mmol/L)	1.25 ± 0.11	1.87 ± 0.22^*
Fasting serum insulin(uIU/mL)	11.32 ± 0.46	20.0 ± 1.77^**
Fasting blood glucose(mmol/L)	5.46 ± 0.09	7.51 ± 0.28^**
HOMA-IR (μIU x mol/L)	2.75 ± 0.14	5.87 ± 0.67^**

HFD high-fat diet, HOMA-IRI homeostasis model assessment of insulin resistance, ND normal diet. The data are shown as the mean ± standard error of the mean of each group; (n = 8); ^* P < 0.05 vs ND group. ^** P < 0.01 vs ND group

ISSN: 1743-7075