|
CON
|
ALM
| |
---|
Pre
|
Post
|
Pre
|
Post
|
P-value
b
|
---|
All subjects (n = 33)
|
hsCRP (mg/dl)
|
0.20 ± 0.19
|
0.29 ± 0.29
|
0.24 ± 0.24
|
0.30 ± 0.29
|
0.796
|
sE-Selectin (ng/ml)
|
43.4 ± 20.7
|
44.0 ± 20.2
|
46.1 ± 18.0
|
42.3 ± 15.5
|
0.121
|
ICAM-1 (ng/ml)
|
223.2 ± 77.4
|
229.2 ± 72.2
|
240.1 ± 89.1
|
230.7 ± 80.9
|
0.225
|
Endothelin-1 (pg/ml)
|
0.98 ± 0.36
|
1.14 ± 0.41
|
1.04 ± 0.39
|
1.16 ± 0.42
|
0.889
|
Nitric oxidde (μmol/l)
|
59.6 ± 35.8
|
72.1 ± 55.3
|
62.5 ± 40.9
|
50.6 ± 26.7
|
0.048
|
Protein carbonyl (nmol/mg)
|
1.00 ± 0.54
|
1.06 ± 0.68
|
1.00 ± 0.65
|
0.72 ± 0.56
|
0.151
|
Oxidized LDL (U/l)
|
32.8 ± 9.9
|
34.8 ± 10.9
|
33.9 ± 10.9
|
35.1 ± 9.9
|
0.736
|
Urinary isoprostanes (ng/mg creatinine)
|
12.2 ± 6.2
|
14.2 ± 9.2
|
11.9 ± 4.2
|
12.2 ± 4.7
|
0.200
|
α-Tocopherol (μmol/l)
|
8.51 ± 3.37
|
9.24 ± 5.45
|
8.86 ± 4.43
|
9.57 ± 5.11
|
0.853
|
Subjects with HbA1c ≤8 (n = 27)
|
hsCRP (mg/dl)
|
0.18 ± 0.19
|
0.29 ± 0.29
|
0.23 ± 0.24
|
0.30 ± 0.30
|
0.789
|
sE-Selectin (ng/ml)
|
42.3 ± 21.7
|
44.5 ± 21.5
|
45.7 ± 18.7
|
41.0 ± 15.4
|
0.026
|
ICAM-1 (ng/ml)
|
222.0 ± 78.6
|
229.1 ± 75.5
|
241.1 ± 92.8
|
231.5 ± 83.7
|
0.263
|
Endothelin-1 (pg/ml)
|
1.01 ± 0.36
|
1.11 ± 0.39
|
1.07 ± 0.38
|
1.16 ± 0.40
|
0.802
|
NO (μmol/l)
|
62.4 ± 37.1
|
71.2 ± 52.1
|
62.1 ± 41.4
|
50.3 ± 28.0
|
0.048
|
Protein carbonyl (nmol/mg)
|
1.13 ± 0.84
|
1.05 ± 0.67
|
0.96 ± 0.64
|
0.75 ± 0.59
|
0.242
|
Oxidized LDL (U/l)
|
31.5 ± 10.1
|
33.8 ± 10.8
|
32.8 ± 11.1
|
33.9 ± 10.2
|
0.653
|
Urinary isoprostanes (ng/mg creatinine)
|
12.7 ± 6.6
|
15.2 ± 9.8
|
11.7 ± 3.8
|
12.0 ± 4.9
|
0.131
|
α-Tocopherol (μmol/l)
|
8.23 ± 2.99
|
8.52 ± 2.83
|
8.25 ± 2.52
|
8.96 ± 3.11
|
0.551
|
-
aData are presented as mean ± SD
-
bP-values illustrate significant difference between post ALM and post CON values, tested using a repeated-measures ANOVA analysis, followed by LSMEANS test