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Table 1 Characteristics of the study subjects with and without non-alcoholic fatty liver disease

From: Lipid accumulation product is a powerful tool to predict non-alcoholic fatty liver disease in Chinese adults

 

Men

P value

Women

P value

Non-NAFLD

NAFLD

Non-NAFLD

NAFLD

N

10,266

8070

 

18,043

4080

 

LAPa

23.7 ± 22.0

62.4 ± 59.7

<0.001

16.6 ± 15.5

49.4 ± 41.2

<0.001

Age (years)a

44.1 ± 15.8

46.8 ± 13.7

<0.001

40.3 ± 12.4

51.8 ± 12.1

<0.001

BMI (kg/m2)

23.1 ± 2.6

26.7 ± 2.6

<0.001

21.7 ± 2.4

25.9 ± 2.9

<0.001

WC (cm)

80.8 ± 7.2

90.5 ± 6.9

<0.001

73.2 ± 7.0

84.8 ± 7.4

<0.001

Current smoker, %

4292 (42.3)

3599 (45.1)

<0.001

669 (3.8)

152 (3.8)

0.871

Physical activity

  

0.135

  

<0.001

 Inactive, %

5947 (60.9)

4587 (59.5)

 

11,127 (67.2)

1938 (53.5)

 

 Moderate, %

2465 (25.2)

2041 (26.5)

 

3931 (23.7)

1035 (28.6)

 

 Active, %

1355 (13.9)

1081 (14.0)

 

1510 (9.1)

647 (17.9)

 

Education

  

0.050

  

<0.001

 Illiteracy/Primary, %

139 (1.4)

91 (1.2)

 

282 (1.6)

201 (5.2)

 

 Middle school, %

1660 (16.7)

1400 (17.9)

 

2977 (17.1)

1345 (35.1)

 

 College or higher, %

8121 (81.9)

6316 (80.9)

 

14,119 (81.2)

2287 (59.7)

 

Drinking, %

3613 (35.2)

3038 (37.6)

0.001

814 (4.5)

129 (3.2)

<0.001

SBP (mmHg)

123.9 ± 14.0

129.3 ± 14.5

<0.001

114.6 ± 14.0

127.5 ± 17.5

<0.001

DBP (mmHg)

76.0 ± 9.5

81.2 ± 10.3

<0.001

70.3 ± 9.3

77.0 ± 10.7

<0.001

FBG (mmol/L)a

5.2 ± 1.0

5.7 ± 1.6

<0.001

5.0 ± 0.7

5.7 ± 1.6

<0.001

Platelet count (109/L)

208.7 ± 50.5

215.9 ± 51.8

<0.001

222.3 ± 53.2

232.0 ± 57.4

<0.001

ALT (U/L)a

26.0 ± 17.3

40.2 ± 26.0

<0.001

17.5 ± 11.5

26.6 ± 18.6

<0.001

TBIL (μmol/L)a

16.6 ± 5.6

15.8 ± 5.4

<0.001

15.2 ± 4.7

14.2 ± 4.2

<0.001

Uric acid (μmol/L)

325.9 ± 74.6

368.4 ± 82.7

<0.001

220.3 ± 59.0

274.1 ± 71.0

<0.001

TG (mmol/L)a

1.4 ± 0.9

2.4 ± 2.1

<0.001

1.0 ± 0.6

1.8 ± 1.4

<0.001

TC (mmol/L)

4.9 ± 0.9

5.3 ± 1.0

<0.001

4.9 ± 0.9

5.4 ± 1.0

<0.001

HDL-C (mmol/L)

1.5 ± 0.4

1.3 ± 0.3

<0.001

1.9 ± 0.4

1.6 ± 0.3

<0.001

Creatinine (μmol/L)

78.3 ± 19.6

77.8 ± 15.6

0.082

54.3 ± 12.1

55.3 ± 11.0

<0.001

Use of antihypertensive, %

807 (7.9)

1153 (14.3)

<0.001

675 (3.7)

742 (18.2)

<0.001

Use of hypoglycemic, %

253 (2.5)

378 (4.7)

<0.001

134 (0.7)

175 (4.3)

<0.001

  1. Abbreviations: LAP lipid accumulation product, BMI body mass index, WC waist circumference, SBP systolic blood pressure, DBP diastolic blood pressure, FBG fasting blood glucose, ALT alanine transaminase, TBIL total bilirubin, TG triglyceride, TC total cholesterol, HDL-C high-density lipoprotein cholesterol
  2. avariables were log-transformed before analysis